USTC Pharmacy Medicinal Garden

University of Science and Technology Chittagong (USTC)

USTC Pharmacy Medicinal Garden

ঘৃতকুমারী (ALOE VERA)

ORIGIN

Aloe vera is believed to have originated in the Arabian Peninsula and later spread naturally and through cultivation to North Africa, the Mediterranean region, South Asia, and the Americas. Today, it is cultivated worldwide in tropical and subtropical regions due to its medicinal and commercial value.

TAXONOMY

  • Kingdom: Plantae

  • Clade: Angiosperms → Monocots

  • Order: Asparagales

  • Family: Asphodelaceae

  • Genus: Aloe

  • Species: Aloe vera (L.) Burm.f.

Synonyms include Aloe barbadensis Miller.

EVOLUTION

Aloe vera evolved as a succulent plant adapted to arid and semi-arid environments. Key evolutionary adaptations include water-storing leaves, thick cuticles, and CAM (Crassulacean Acid Metabolism) photosynthesis, which reduce water loss and allow survival under drought conditions.

DESCRIPTION

Aloe vera is a short-stemmed perennial succulent.

  • Leaves: Thick, fleshy, lance-shaped, green to gray-green with serrated margins

  • Gel: Clear, mucilaginous inner pulp rich in bioactive compounds

  • Flowers: Yellow or orange tubular flowers arranged on tall spikes

  • Roots: Fibrous and shallow

ECOLOGY

The plant grows best in dry, warm climates.

  • Highly drought-tolerant

  • Prefers sunny locations

  • Poor tolerance to frost and waterlogging

  • Supports pollinators such as bees and birds during flowering

CULTIVATION

Aloe vera is widely cultivated both commercially and domestically.

  • Propagation: Offsets (pups) and suckers

  • Climate: Tropical to subtropical

  • Soil: Well-drained sandy or loamy soil

  • Water: Minimal; overwatering causes root rot

Harvesting usually begins 8–12 months after planting.

TRADITIONAL USES

Traditionally, Aloe vera has been used for:

  • Treating burns, wounds, and skin infections

  • Improving digestion and bowel movement

  • Hair and scalp care

  • Cosmetic applications for skin hydration

It has been used in Ayurveda, Unani, Chinese, and folk medicine systems.

MEDICINAL USES

Medically, Aloe vera is known for:

  • Wound healing and burn treatment

  • Anti-inflammatory and antimicrobial effects

  • Laxative action (from aloe latex, used cautiously)

  • Supporting immune function and digestive health

Aloe gel is widely used in pharmaceuticals, cosmetics, and nutraceuticals.

RESEARCH

Scientific research has identified:

  • Bioactive compounds: Aloin, aloe-emodin, polysaccharides (acemannan), vitamins, enzymes, and amino acids

  • Pharmacological activities:

    • Antioxidant

    • Antimicrobial

    • Anti-inflammatory

    • Antidiabetic

    • Wound-healing and skin regeneration

Clinical studies support its topical use, while oral use requires controlled dosage.

BIOLOGY

  • Life form: Perennial succulent

  • Photosynthesis: CAM pathway

  • Reproduction: Vegetative propagation mainly; flowering is seasonal

  • Growth habit: Rosette-forming with continuous leaf regeneration

TOXICITY

Aloe vera is generally safe when used topically.

  • Oral use of aloe latex can cause abdominal cramps, diarrhea, and electrolyte imbalance

  • Long-term or excessive ingestion may be harmful

  • Not recommended for pregnant women and children without medical supervision

CONCLUSION

Aloe vera (Ghritkumari) is one of the most important medicinal plants globally, valued for its therapeutic, cosmetic, and commercial applications. Its traditional uses are strongly supported by modern scientific research, particularly for skin and wound care. However, proper processing, dosage control, and clinical supervision are essential to ensure safety, especially for internal use.

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