USTC Pharmacy Medicinal Garden

University of Science and Technology Chittagong (USTC)

USTC Pharmacy Medicinal Garden

ধুতুরা (DATURA METEL)

ORIGIN

Datura metel is believed to have originated in tropical Asia, particularly the Indian subcontinent. Today, it is widely distributed across Asia, Africa, and the Americas. The plant has long-standing religious, medicinal, and cultural significance in South Asia and is traditionally associated with Lord Shiva in Hinduism.

TAXONOMY

  • Kingdom: Plantae

  • Division: Angiosperms

  • Class: Eudicots

  • Order: Solanales

  • Family: Solanaceae

  • Genus: Datura

  • Species: Datura metel L.

EVOLUTION

Datura metel belongs to the Solanaceae family, which includes plants such as potato, tomato, chili, and tobacco.

  • Evolved strong chemical defense mechanisms

  • Production of tropane alkaloids (atropine, scopolamine) to deter herbivores

  • Adapted to open, disturbed, and warm habitats

  • Toxicity provided an evolutionary advantage by reducing predation

DESCRIPTION

  • Plant type: Shrub-like annual or short-lived perennial herb

  • Height: 1–2 meters

  • Leaves: Large, ovate, dark green, with wavy margins

  • Flowers: Large, trumpet-shaped; white, purple, or violet; fragrant at night

  • Fruit: Globular, spiny capsule

  • Seeds: Numerous, small, brown to black

ECOLOGY

  • Climate: Tropical and subtropical

  • Soil: Well-drained sandy or loamy soil

  • Sunlight: Full sun

  • Habitat: Roadsides, wastelands, agricultural margins

The plant is hardy and grows easily in disturbed soils.

CULTIVATION

  • Propagation: Seeds

  • Sowing time: Spring or early monsoon

  • Maintenance: Minimal

  • Growth habit: Fast-growing

Cultivation is generally limited due to the plant’s toxicity.

TRADITIONAL USES

Ayurvedic & Folk Medicine

  • Treatment of asthma and bronchitis (strictly controlled doses)

  • Pain relief and muscle relaxation

  • External application for wounds, boils, and inflammation

Religious Use

  • Offered in rituals dedicated to Lord Shiva

  • Used in traditional tantric practices

MEDICINAL USES

Use only under professional supervision

Therapeutic Properties

  • Antispasmodic

  • Analgesic (pain-relieving)

  • Sedative

  • Bronchodilator

Medicinal Parts Used

  • Leaves

  • Seeds

Modern medicine uses purified compounds rather than raw plant material.

RESEARCH

Major Bioactive Compounds

  • Atropine

  • Scopolamine

  • Hyoscyamine

Scientific Findings

  • Strong anticholinergic effects

  • Used in modern medicine for:

    • Motion sickness (scopolamine)

    • Muscle spasms

    • Pre-anesthetic medication

  • Extensive research confirms both therapeutic potential and high toxicity

BIOLOGY

  • Pollination: Insects, especially nocturnal moths

  • Chromosome number: 2n = 24

  • Life cycle: Annual or short-lived perennial

  • Reproduction: By seeds

TOXICITY

Extremely toxic plant

Symptoms of Poisoning

  • Dry mouth and throat

  • Dilated pupils

  • Hallucinations and delirium

  • Rapid heartbeat

  • Respiratory failure

  • Coma or death (in severe cases)

Self-medication is dangerous and potentially fata

CONCLUSION

Datura metel is a powerful but highly dangerous medicinal plant.
While it has historical and pharmacological importance, its narrow safety margin makes unsupervised use extremely risky. Today, its value lies mainly in pharmaceutical research and controlled medical applications, not in home remedies.

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